Microdose Leuprolide
Description:
Leuprolide Acetate (Lupron®) is related to a naturally occurring hormone called gonadotropin-releasing hormone (GnRH). Leuprolide Acetate has also been used to treat endometriosis, uterine fibroids, early puberty, and as part of the process to stimulate multiple eggs for assisted reproductive technologies. The pharmacist according to the physician’s instructions compounds Microdose Leuprolide. Microdose Leuprolide is commonly prepared as the 40mcg/0.1ml or 50mcg/0.1ml. These preparations are a diluted concentration of the prescription Leuprolide Acetate 1mg/0.2ml.
How It Works:
Leuprolide Acetate is administered as a subcutaneous injection using insulin syringes. Insulin syringes are used because the measurement on the syringe is in units (i.e.: 10 units is equivalent to 0.1ml/cc). For the role it plays in assisted reproductive technologies, Leuprolide Acetate is used to reduce the amount of estrogen and testosterone in the body. This decrease in estrogen production will prevent ovulation and may stop menstrual periods.
Potential Side Effects:
Side effects that may occur include: hot flashes or sweating, mood swings, vaginal dryness, decreased libido, nausea, vomiting, breast tenderness, insomnia, headaches, and injection site reaction (redness, itching, swelling at the injection site).
If you experience an allergic reaction: difficulty breathing; closing of your throat; swelling of your lips, tongue or face; or hives; seek emergency medical attention immediately. And if at any time you experience bone pain, difficulty urinating, numbness, tingling or weakness in the arms or legs contact your physician immediately.
PLEASE NOTE: If these or any other side effects occur, contact your physician.
Storage:
Microdose Leuprolide must be stored in the refrigerator. Do not freeze. Microdose Leuprolide has a 30-day expiration date from the day of compounding (the expiration will be marked on the vial).