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HUMAN CHORIONIC GONADOTROPIN (hCG) NOVAREL® PREGNYL®
Description:
Pregnyl and Novarel contain human chorionic gonadotropin (hCG). HCG is a naturally occurring hormone produced by the placenta. It is indicated for the induction of ovulation and pregnancy in the anovulatory, infertile women in whom the cause of anovulation is secondary and not due to primary ovarian failure.
How It Works:
HCG is administered as an injection intramuscularly or subcutaneously depending on the physician’s instructions. HCG is virtually identical to that of pituitary luteinizing hormone (LH). During the normal menstrual cycle, LH participates with follicle stimulating hormone (FSH) in the development and maturation of the normal ovarian follicle, and the mid-cycle LH surge triggers ovulation. During an assisted reproductive cycle (ART), hCG is used to induce egg maturation and trigger ovulation (the release of an egg(s) from the ovary) in women who have been treated with ovulation inducing medications.
Potential Side Effects:
Side effects that may occur include: headache, irritability, restlessness, depression, fatigue, enlargement/rupture of pre-existing ovarian cysts, and fluid retention. The risk of ovarian hyperstimulation syndrome (OHSS) should be discussed with your physician prior to treatment. Early warning signs include severe pelvic pain, nausea, vomiting and weight gain.
If you experience an allergic reaction: difficulty breathing; closing of the throat; swelling of the lips, tongue or face; or hives; seek emergency medical attention immediately. And if at any time you experience: pain, warmth, redness, numbness, or tingling in an arm or leg; confusion, severe dizziness or severe headache, seek medical attention immediately.
PLEASE NOTE: If these or any other side effects occur, contact your physician.
Storage:
Pregnyl and Novarel should be stored at controlled room temperature 59-86ºF. After mixing, it must be stored in a refrigerator and used within 30 days or 60 days depending on the product.
HUMAN CHORIONIC GONADOTROPIN (hCG)
NOTE: These medications may be given as a subcutaneous injection or an intramuscular injection depending on your physician's orders. Instructions for both injections are included..
Mixing
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Pop off the plastic top of powdered medication and diluent (liquid).
Swab the top of each vial with an alcohol pad to prevent contamination.
Select a 3cc syringe with 1 1/2" needle for mixing. Twist to secure needle.
Using your syringe, draw back 1cc of air into the syringe.
Firmly insert the needle through the rubber stopper into the vial of diluent . Invert, or turn upside down, the vial and syringe as one complete unit and depress the air into the vial in order to equalize the pressure, which will make withdrawal of the diluent easier. Once you depress the plunger of the air-filled syringe into the vial, make sure the tip of the needle is BELOW the liquid level and pull the plunger to withdraw 1cc of the diluent.
NOTE: These medications may be given as a subcutaneous injection or an intramuscular injection
depending on your physician's orders. Instructions for both injections are included.
Slowly and cautiously deposit the diluent into the vial of powdered medication. Rotate the vial between your thumb and index finger until the solution is clear. Withdraw the newly mixed medication back into the syringe. Remove the syringe from the vial. .
Invert the syringe so the needle is pointing upwards and tap the syringe to force any air bubbles to the top. Depress the plunger to expel the air.
If you are now ready for your subcutaneous injection, recap and remove the mixing needle by twisting and replace it with the smaller subcutaneous injection needle (usually 1/2” needle). PROCEED TO SUBCUTANEOUS INJECTION INSTRUCTIONS
If you are now ready for your intramuscular injection, recap and remove the mixing needle by twisting and replace it with the intramuscular injection needle (usually 1 1/2" needle). PROCEED TO INTRAMUSCULAR INJECTION INSTRUCTIONS |
Subcutaneous Injection Instructions
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Cleanse your selected SUBCUTANEOUS injection site with an alcohol wipe and allow to dry.
While holding the syringe with your dominant hand between your thumb and finger
(as you would a pencil), pinch the skin (with your other hand) at the site you have selected.
With a quick, dart-like motion, insert the entire needle (up to the hub of the syringe)
at a 90° or a 45° angle and depress the plunger slowly and carefully.
After the injection is complete, quickly pull out the needle. If bleeding, apply pressure to the injection site with a sterile gauze pad. If discomfort occurs after your injection, you may gently massage the injection site to alleviate your discomfort.
After injecting the medication dispose of the syringe into the Sharps waste container.
It is unnecessary to recap the needle as this could cause injury |
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Intramuscular Injection Instructions
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Cleanse your selected INTRAMUSCULAR injection site with an alcohol wipe and allow to dry.
Hold the syringe with your dominant hand between your thumb and index finger (as you would a pencil). With your other hand, firmly stretch your skin at the selected injection site. Make sure you are using the intramuscular needle (usually 1 1/2 ”).
NOTE: To minimize bruising, firmly stretch the skin.
Using either hand to stabilize the syringe, pull back slightly on the plunger and watch for blood in the syringe. (This is rare). You may feel slight resistance or see a small bubble - this is normal. If blood is not seen in the syringe, the needle is inserted properly. If blood appears in the syringe, DO NOT INJECT YOUR MEDICATIONS.
Depress the plunger slowly and steadily.
Pull the syringe out in one motion.
After injecting the medication, dispose of the needle and syringe into the Sharps waste container. It is unnecessary to recap the needle as it could cause injury to yourself.
Apply pressure to the site with a gauze pad and gently massage the area to help disperse the medication and relieve discomfort. Apply a bandage if necessary. |
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